Immunology
In vivo Pharmacology Service Sheet
Preclinical Services Sheet
Pharmaron's highly experienced professionals in the Immunology and Assay Support Department are fully equipped to provide our clients with a wide range of immunology services. With their in-depth GLP compliance knowledge and the advanced instrumentation at their disposal, our staff can deliver the immunology services needed to support biologic and large molecule product development.
Assay Development and Validation
We develop and validate assays according to US FDA/ICH guidelines with the following assay formats:
- Ligand binding (ELISA, EIA, RIA)
- Cell-based
- FACS-based
- Receptor-binding
- Biochemical
Bioanalytical Sample Testing
Our testing service is fully GLP-compliant, ensuring timely delivery of high-quality results to our clients.
- Toxicokinetic testing for large molecules and biologics
- Immunogenicity testing
- Biomarker testing
- Clinical sample testing
Immunotoxicity Testing
We can provide standard and supplemental immunotoxicity tests, in accordance with ICH guidelines, to determine adverse effects of human pharmaceuticals on the immune system.
- Hematological analysis
- Immune system organ weight and/or histology
- Quantification of serum globulins
- Immunophenotyping of leukocytes by FACS
- Determination of NK cell activity
- Evaluation of T-cell dependent antibody response by KLH immunization