Oncology

  In vivo Pharmacology Service Sheet

Currently, we can provide services in in vivo oncology including cell line derived and patient tumor-derived xenograft models.  The following is a list of services we can provide in the in vivo oncology therapeutic area:
  • Validated 300 tumor models
  • Type of Studies
    • Maximum tolerated dose (MTD)
    • Dose-response efficacy studies
    • Combination therapies using cytotoxic/ targeted/antibody-based therapeutics
    • PK/PD study
    • Establishment of resistant model
  • Translational Medicine
    • Collection of frozen human tumor samples
    • Collection of paraffin-embedded human tumor tissue sections
    • Exome sequencnig information for primary tumor samlpes
    • Mutational, mRNA and protein analysis
    • Biomarker/target evaluation