• Synthetic-Chemistry_11
  • Synthetic-Chemistry_2-1-2

Small-Molecule Synthetic Chemistry

Pharmaron chemists are skilled in the latest methods in synthetic organic chemistry, including asymmetric synthesis.  We have a demonstrated expertise in the design and preparation of multi-step targets on scales ranging from milligrams to kilograms.

Organic Synthesis (mg to hundreds of grams)

  • Building blocks and reference compounds
  • Novel compounds of discovery/medicinal chemistry programs
  • Scale up to support in vivo efficacy and toxicity studies

Chiral ChemistryPharmaron “Chiral Suite”

  • Asymmetric synthesis
  • Chiral resolution: Kilogram scale
  • Chiral separation (SFC, HPLC): mg – hundreds of grams

Bioorganic Chemistry

  • Nucleosides & nucleotides, Carbohydrate, Peptides
  • Lipid, Antibody Drug Conjugates (ADC)

Library Chemistry

  • General, diversity-based libraries for corporate compounds collection
  • Focused or target-based libraries (for particular therapeutic or target interests)
  • Project libraries: SAR-oriented libraries to support medicinal chemistry programs
  • Fragment-based libraries

– See more at: http://www.pharmaron.com/service/synthetic-chemistry/#sthash.MV2OI8rI.dpuf