Found 3 results for OCT1 HEK293.



...solubility assessment at an additional charge. Percent inhibition is calculated as 100 x [1-(IROCT1-IRVC)TC / (IROCT1 – IRVC)0], where IROCT1 is the influx rate of MPP+ in OCT1-transfected cells, IRVC is the influx rate...

Discovery in vitro ADMET

...OATP1B3, OAT1, OAT3, OCT1, OCT2, OATP2B1, OATP1A2, MATE1, MATE2, PEPT1, NTCP, ASBT) Hepatic uptake using media-loss method Download our poster about our permeability assay platform Metabolic Stability and Identification Metabolic...

Regulatory in vitro ADMET Studies

...(PAMPA, Caco-2, MDCK and transfected MDCK cell lines) Transporter investigation on substrate and inhibitor evaluation (P-gp, BCRP, BSEP, MRP2, MRP3, MRP4, OATP1B1, OATP1B3, OTAP2B1, OAT1, OAT3, OCT1, OCT2, MATE1, MATE2K,...