Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ

Pharmaron publication on benzoxazepines suppressing IL-17 release in TH17 cells via nuclear receptor RORy binding

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Authors: Roine I. Olsson, Yafeng Xue, Stefan von Berg, Anna Aagaard, Jane McPheat, Eva L. Hansson, Jenny Bernström, Pia Hansson, Johan Jirholt, Hanna Grindebacke, Agnes Leffler, Rongfeng Chen, Yao Xiong, Hongbin Ge, Thomas G. Hansson, Frank Narjes

ChemMedChem. 2016 Jan 19;11(2):207-16.

DOI: 10.1002/cmdc.201500432

Access the publication at:https://pubmed.ncbi.nlm.nih.gov/26553345/