A GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in vivo Profile

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Authors: Elisia Villemure, Matthew Volgraf, Yu Jiang, Guosheng Wu, Cuong Q. Ly, Po-Wai Yuen, Aijun Lu, Xifeng Luo, Mingcui Liu, Shun Zhang, Patrick J. Lupardus, Heidi J. A. Wallweber, Bianca M. Liederer, Gauri Deshmukh, Emile Plise, Suzanne Tay, Tzu-Ming Wang, Jesse E. Hanson, David H. Hackos, Kimberly Scearce-Levie, Jacob B. Schwarz, Benjamin D. Sellers

ACS Med Chem Lett. 2016 Oct 31;8(1):84-89

DOI: 10.1021/acsmedchemlett.6b00388

Access the publication at: https://pubmed.ncbi.nlm.nih.gov/28105280/