Poster featuring details about establishing an untargeted metabolomics workflow for analyzing spent media by LC-MS. It highlights how bioanalytical development enhances the process. A preview of the poster's content is on the left, and a call-to-action to download it is on the right. Pharmaron logo at the bottom.

Poster Authors:

Charlotte Hands & Patrick Hoering

Pharmaron Gene Therapy l Estuary Commerce Park, Speke, Liverpool, L24 8RB, UK

Analysing the metabolome can identify metabolites, which can be validated using targeted LC-MS and used to improve yield or quality of AAV. This work is the first step to identify compounds which correlate with gene therapy products during bioreactor operation.

Capabilities