Ocular Hypertension Model For Glaucoma Research In Minipigs

Poster Authors:

Sudan Puri¹; Pamela Ko^1,2; James Lee¹; Vivien Trenti¹; Sujata Rijal¹; Vatsala Naageshwaran¹; Sandeep Kumar¹; Glenwood G. Gum¹

¹Ophthalmology, Pharmaron US Lab Services, 2820 Loker Ave E, Carlsbad, United States.

²Ophthalmology, Animal Samaritans Hospital, Thousand Palms, CA, United States

Pig eyes share many anatomical and physiological similarities with human eyes, including holangiotic retinal vasculature, cone photoreceptors presence in the outer retina, no tapetum lucidum, and a similar scleral thickness, rendering them a valuable model for glaucoma research.

The purpose of this study was to establish an ocular hypertension (OHT) model via multiple episcleral vein cauterizations to assess changes in intraocular pressure (IOP), retinal structure and function in Yucatan minipigs.

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Knowledge Center

Ocular Testing Services

CGT Ophthalmology

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