Porcine Retinal Neovascularization Model For Therapy Testing

Poster Authors:

Sandeep Kumar; Xiaohui Zhang; Sudan Puri; Jenny Walters; James Lee; Vivian Trenti; Vatsala Naageshwaran; Glenwood G. Gum

Ophthalmology, Pharmaron US Lab Services, 2820 Loker Ave E, Carlsbad, CA 92010

Human and porcine eyes share many anatomical and physiological characteristics, including size of the eye, holangiotic retinal vasculature, no tapetum, cone photoreceptors in the outer retina and a similar scleral thickness. These similarities make porcine species a preferred model for ocular toxicology and pharmacology studies. Therefore, our purpose was to establish a chronic retinal neovascularization (RNV) porcine model that can be employed to evaluate the efficacy of anti-neovascular therapies.

Capabilities

Knowledge Center

CGT Ophthalmology

Ocular Testing Services

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