Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase

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Authors: Nicole Blaquiere, N; Castanedo, G; Burch, J; Berezhkovskiy L; Brightbill, H; Brown S; Chan, C; Chiang, P; Crawford, J; Dong, T; Fan, P; Feng, J; Ghilardi, N; Godemann, R; Gogol, E; Grabbe, A; Hole, A; Hu, B; Hymowitz, S; Ismaili, MHA; Le, H; Lee, P; Lee, W; Lin, X; Liu, N; McEwan, P; McKenzie B; Silvestre, H; Suto, E; Sujatha-Bhaskar S; Wu, G; Wu, L; Zhang, Y; Zhong,Z; Staben, S.

J Med Chem. 2018 Aug 9;61(15):6801-6813

DOI: 10.1021/acs.jmedchem.8b00678

Access the publication at:https://pubmed.ncbi.nlm.nih.gov/29940120/