Structure-based design of tricyclic NF-κB inducing kinase (NIK) inhibitors that have high selectivity over phosphoinositide-3-kinase (PI3K)
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Authors: Castanedo, G*; Blaquiere, N; Beresini, M; Bravo, B; Brightbill, H; Chen, J; Cui, H, Eigenbrot, C; Everett, C; Feng, J; Godemann, R; Gogol, E; Hymowitz, S†; Johnson, A; Kayagaki, N; Bir Kohli, P; Knüppel, K; Kraemer, J; Krüger, S; Loke, P; McEwan, P; Montalbetti, C; Roberts, D; Smith, M; Steinbacher, S; Sujatha-Bhaskar, S; Takahashi, R; Wang, X; Wu, L; Zhang, Y; and Staben, S.
J Med Chem. 2017 Jan 26;60(2):627-640
DOI: 10.1021/acs.jmedchem.6b01363
Access the publication at:https://pubmed.ncbi.nlm.nih.gov/28005357/