Process Chemistry

The process chemistry team provides a broad range of services for API development from lead optimization through to NDA in our China and UK facilities.

• Discovery and development of new and existing synthetic routes, fit-for-purpose optimization and scale-up for preclinical and early phase clinical evaluation
• Polymorph and salt/co-crystal screening for selection of an appropriate solid form for API development
• Crystallization of API and intermediate for process development
• Development of synthetic routes and scalable processes for complex organic molecules and APIs, such as macrolides, nucleotides and nucleosides including those with synthetic sequences over 20 steps
• Definition and study of critical process parameters to support validation of chemical processes for GMP/non-GMP production of APIs
• Discovery and development of cost effective, safe and environmentally friendly synthetic routes for commercial production of intermediates and APIs from kilograms to ton scales

Learn more about Pharmaron's Process Development and Manufacturing Services