Integrated in vitro and in vivo ADME
Integrated in vitro and in vivo ADME to Enable Rapid Decision Making
Understanding the mechanisms, rates, and routes of drug ADME is essential in discovery and development. Whether the focus is on lead optimisation, candidate identification or profiling, or preparing for Investigational New Drug (IND) or New Drug Application (NDA) regulatory submissions, Pharmaron’s integrated in vitro and in vivo ADME services can deliver extensive support.
Pharmaron works closely with our clients as a fully integrated partner, guiding them through the entire process, providing timely high-quality data, while simplifying and expediting program decisions. Our strong scientific experience allows us to build consultative relationships to drive NCEs and NBEs through Discovery and Development, and beyond.
View our on-demand webinars within our DMPK series, covering a spectrum of interesting DMPK topics.
Capabilities
A fully integrated partner:
- Our cross-functional team of experienced DMPK scientists and leaders covers all aspects of DMPK from drug discovery to regulatory submission, and everything in between.
- Our consultancy-based approach provides strategic and experimental guidance and continuity.
- Our facilities support non-GLP as well as GLP and GCP-compliant bioanalytical services minimizing the need for technology transfers.
- Data are delivered to meet all requirements, spanning rapid data upload during DMTA cycles to regulatory reports.
- Pharmaron offers a one stop shop for continuous solutions reducing the cost and complexity associated with sourcing solutions from multiple specialist vendors.
Capabilities
- In vitro ADME
- Rodent PK
- Non-Rodent PK
- In vivo ADME PKPD
- Metabolite Identification
- IND/DDI Studies
- Metabolite Profiling (MIST)
Access our Integrated ADME Service Infographic
