Biochemistry

biochemical assays at Pharmaron are conducted with acoustic technology

Biochemical Assays

Pharmaron is the leading provider of biochemical assay services employing state-of-the-art technology to deliver precise and reproducible results with a turnaround time of just 3 days for standard biochemical assays.  

Our diverse array of cutting-edge technologies cover all needs of biochemical testing, including primary screening, counter-screening, and orthogonal testing by analyzing binding, conformational changes, and enzyme activities.

Our specialized assay development team crafts bespoke biochemistry assays tailored to client specifications, supporting a wide range of applications from high-throughput screening, kinetic readouts, and characterization of a compound’s mechanism of action. 

We provide flexible reporting for biochemistry assay results, adjusting the format and uploading specifications to our clients. We use CEDAR as our central data management hub which further enhances the efficiency of our services. The cherry-picking of compounds and provision of custom-tailored biochemical assay services are part to our daily routines, reflecting our dedication to meet and exceed our clients’ expectations with our flexibility.

Targets

  • Kinases
  • GPCRs
  • Nuclear receptors
  • GTPases
  • Proteases
  • Phosphatases
  • DNA Polymerases
  • DNA repair enzymes
  • DNA repair enzymes
  • Epigenetic regulatory enzymes
  • Metabolic enzymes
  • Hydrolases
  • E3 ligases
  • Deubiquitinases
  • Phosphodiesterases
  • Oxidases/reductases
  • and more.
The use of the envision instrument helps conduct biochemical assays

Technologies

  • Absorbance
  • FI
  • AlphaScreen
  • AssayQuant
  • DELFIA
  • IMAP
  • TR-FRET (HTRF, Ulight, etc.)
  • Luminescence
  • ELISA/MSD
  • Radiochemical-based
  • LC/MS
  • ADP-Glo
  • Mobility shift assay
  • Nucleotide Exchange Assay

Fully Automated High Throughput Biochemical and Cell-based Screening with the Explorer G3 Suite.

A woman in a lab coat operates scientific equipment on the left side, with the text "Fully Automated High-Throughput Screening Services" displayed. On the right, "Watch Our Robots in Action" appears above the Pharmaron logo, highlighting our expertise in radiolabelled ADME.