14C Radiolabels and AMS for Biologics

Our team offers radiolabelling of biologics with 14C combined with Accelerator Mass Spectrometry (AMS) analysis to provide pharmacokinetic (PK) and tissue disposition data in animal models. Non-clinical Studies

  • Analysis of parent compound in a wide range biological matrices (i.e. plasma, skin, kidney, liver, spleen, bile, excreta)
  • Analysis of total 14C in all tissues/cells/biological fluids and expired air
  • Radiolabelled cytokine/protein target turn-over studies
  • Analysis of radiolabelled biologics in toxicology species
  • Oligonucleotides, ADCs, therapeutic proteins, peptides, fusion proteins

Disposition of Radiolabelled Biologics
3H and 14C Radiolabels (RadioTag)

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