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An Automated Workflow for Phenotypic Drug Discovery with Cell Painting
In this poster we present Pharmaron’s comprehensive cell profiling service enabling economic and systematic phenotypic drug discovery.
The service integrates four key components
Cell culturing and drug transfer
Cell painting
High-content imaging
Machine learning-assisted image analysis
In a pilot study on 390 kinase inhibitors, we confirm the power of this phenotypic drug discovery approach to categorize test articles with similar targets or mode of actions (MoA).