Medicinal Chemistry

Medicinal Chemistry Services

Pharmaron’s medicinal chemistry team provides our partners with reliable data and a quick turnaround to reduce the time between decision points and keep your drug discovery programs moving ahead.

With expertise from hit identification to preparation for IND filing, Pharmaron’s medicinal chemistry team understands our partners’ needs and are well equipped to help advance drug discovery programs. We have experience with a wide range of therapeutics areas.

  • Scaffold design for hit identification (ID)
  • Preliminary IP analysis on newly designed scaffolds
  • Synthesis of focused libraries for LG and LO
  • SAR development based on in vitro biology & ADMET
  • SAR optimization to improve PK and safety profile of chemical lead
  • Computer-aided drug design (CADD) and diversity analysis
  • Non-GMP scale-up to support in vivo efficacy and toxicity studies
  • Patent application preparation
  • Recommend DMPK and in vitro toxicology studies for compound advancement
  • Project management
Two people reviewing paperwork

Patent Filing Assistance

Pharmaron can assist with the patent filing process with the help of the many databases our team has access to, including:

  • Reaxys
  • SciFinder
  • ACS journal access
  • Additional scientific journals