Oncology Animal Models
Oncology Animal Model Services
Our in vivo pharmacology team is experienced with oncology animal model establishment and validation for efficacy screening, in vivo pharmacology profiling, PK/PD and MOA studies.
The team is supported by internal PK/bioanalytical, ex vivo pharmacology and in vitro biology teams to provide integrated services.
Learn more: Oncology and Immuno-oncology in vivo Pharmacology Solutions
Study Types:
- Development and validation of disease models
- Maximum tolerated dose studies
- Dose range finding studies
- Efficacy screening studies
Capabilities
Oncology Disease Models
- Large cancer cell line (2,000+) and tissue bank
- 1,000+ fully validated cell-line derived xenograft (CDX) models
- 85+ synthetic tumor models with complete immune profile and SOC data
- 350+ patient-derived xenograft (PXD) models with patient history
- 160+ orthopedic models of more than 15 cancer types including intracranial implantation
Analytical Platforms
- Drug exposure in blood and tissue
- Specific biomarkers in blood and tissue
- Gene or protein analysis platforms
- FACS analysis of cells, blood and tissue samples
- Histology, biochemistry, IHC
- Blood sample analysis with biochemistry and hematology
- Analysis of body fluid, urine and feces
Learn more about Pharmaron’s Oncology and Immuno-Oncology Capabilities
