ex vivo Pharmacology & Biomarkers

Mesoscale discovery is employed to study the mode of action after performing cell-based functional assays.

ex vivo Pharmacology & Biomarkers Services

The purpose of ex vivo analysis is to confirm the in vivo effect of test articles and to find out the correlation between in vivo efficacy and biomarkers. 

Our ex vivo team has years of experience and can support your drug discovery program by providing ex vivo pharmacology & biomarker analysis services.

Study sample types include blood, plasma, cerebral spinal fluid (CSF), tissue extraction, urine and feces and bronchoalveolar lavage fluid (BALF).

Gene or Protein Analysis Platforms

  • RT-PCR
  • ELISPOT
  • Auto MACS Pro
  • ELISA
  • Alpha LISA
  • WB
  • MSD
  • Luminex
        Close-up of a microscope's objective lenses used in bioanalytical development. The lenses are labeled with different magnification levels, including 10x, 40x, and 100x. The microscope stage, where slides for genetic toxicology studies are placed for observation, is also partially visible. The background is blurred.

Histology, Histochemistry and Immunohistochemistry – Frozen/Paraffin Sections

  • Tissue section or TMA slides
  • Enzyme or fluorescence labeling
  • Multiple antibodies labeling
  • Antibody characterization for specificity or staining condition
  • Method development – adopt staining protocol from manual to auto-stainer system
Close-up of an automated laboratory equipment that holds and processes multiple samples. The machine, essential for bioanalytical development, has a robotic arm, precise controls, and various slots for vials, showcasing advanced technology used for high-throughput analysis or testing.

Additional ex vivo Pharmacology & Biomarkers Services

  • FACS analysis of cells, blood and tissue samples
  • Clinical pathology
    • Blood biochemistry and hematology
    • Bone marrow smear
    • Blood smear and staining