ex vivo Pharmacology & Biomarkers Services

The purpose of ex vivo analysis is to confirm the in vivo effect of test articles and to find out the correlation between in vivo efficacy and biomarkers.

Our ex vivo team has years of experience and can support your drug discovery program by providing ex vivo pharmacology & biomarker analysis services.

Study sample types include blood, plasma, cerebral spinal fluid (CSF), tissue extraction, urine and feces and bronchoalveolar lavage fluid (BALF).

Capabilities

Animal Disease Models

ex vivo Pharmacology & Biomarkers

A scientist in blue gloves handles a microplate, preparing it for analysis in an MSD (Meso Scale Discovery) system for biomarker or drug discovery testing.

Gene or Protein Analysis Platforms

RT-PCR
ELISPOT
Auto MACS Pro
ELISA
Alpha LISA
WB
MSD
Luminex

Close-up of a microscope lens focusing on a sample slide, used for conducting ex vivo assays in biosciences research.

Histology, Histochemistry and Immunohistochemistry – Frozen/Paraffin Sections

Tissue section or TMA slides
Enzyme or fluorescence labeling
Multiple antibodies labeling
Antibody characterization for specificity or staining condition
Method development – adopt staining protocol from manual to auto-stainer system

A close-up of automated lab equipment processing samples for in vivo pharmacology research, focusing on pharmacokinetics and drug interactions.

**Additional ex vivo Pharmacology & Biomarkers Services**

FACS analysis of cells, blood and tissue samples
Clinical pathology
- Blood biochemistry and hematology
- Bone marrow smear
- Blood smear and staining

Related Services

Two scientists in lab coats and masks conduct an experiment using a pipette in a biosciences lab, with equipment and supplies on the counter.

Learn more about Pharmaron’s biosciences services

Pharmaron’s in vitro biology, in vivo pharmacology, DMPK and discovery biologics services support drug discovery and early development programs. Integration of these functions, together with laboratory chemistry, CMC and safety assessment, successfully deliver preclinical candidates and IND packages.

Blue DNA Helix Molecule

Learn more about Pharmaron’s integrated drug discovery and development services

Pharmaron provides a complete integrated platform from drug discovery to proof of concept (“POC”). Our industry knowledge, strong execution tactics and end-to-end solutions shorten the drug discovery and development cycle.