Radiolabelling and Radiosynthesis

A scientist wearing blue gloves carefully pours blue liquid from a flask into a test tube in a laboratory setting. The background is blurred, emphasizing the precise handling of chemicals. in radiosynthesis and radiolabelling services for ADME

Radiolabelling and Radiosynthesis Services

Pharmaron’s service offerings in radiolabelling and radiosynthesis cover the entire radiosynthesis process, which includes selecting the label position in the molecule, optimizing the radiosynthesis chemistry pathway, radiosynthesis, final product analysis, and repurification or recycling options.

A scientist in blue gloves carefully measures a liquid in a graduated cylinder, performing tritium radiolabelling and radiosynthesis under controlled conditions.

Radiosynthesis Services

  • 14C radiosynthesis (custom)
  • 3H radiosynthesis (custom)
  • GMP preparation of 14C radiolabelled drug substance (14C-API) and radiolabelled drug product (investigational medicinal product or IMP)
  • Non-GMP clinical-grade repurified 14C-API (for use in micro tracer or microdosing studies)
  • 3H and 14C rapid covalent radio-tagging techniques
A scientist in protective gear works on radiolabelling and radiosynthesis in a lab, surrounded by specialized equipment and fume hoods.

Custom Carbon-14 Radiosynthesis Services

  • Volatile compounds
  • Aromatics and heterocyclics
  • Chiral compound
  • Salt formation
  • Amino acids and peptides
  • Biomolecules using fermentation (Class 1 containment)
  • Covalent radiolabelling techniques with 14C (RadioTag) for macromolecules
Pharmaron service overview for manufacturing Carbon-14 radiolabeled drug substances and products, highlighting capabilities, services, and specialties on a gradient background.

Read about Pharmaron’s approach for uncovering mechanisms of drug resistance in cancer cells

Scientists in full protective gear work in a dimly lit lab, focusing on oligonucleotides, radiolabeling, and metabolism studies within a sterile environment.

Learn about Pharmaron’s capability to synthesize radiolabelled oligonucleotides.