Radiolabelling and Radiosynthesis
Radiolabelling and Radiosynthesis Services
Pharmaron’s service offerings in radiolabelling and radiosynthesis cover the entire radiosynthesis process, which includes selecting the label position in the molecule, optimizing the radiosynthesis chemistry pathway, radiosynthesis, final product analysis, and repurification or recycling options.
Capabilities
Radiosynthesis Services
- 14C radiosynthesis (custom)
- 3H radiosynthesis (custom)
- GMP preparation of 14C radiolabelled drug substance (14C-API) and radiolabelled drug product (investigational medicinal product or IMP)
- Non-GMP clinical-grade repurified 14C-API (for use in micro tracer or microdosing studies)
- 3H and 14C rapid covalent radio-tagging techniques
Custom Carbon-14 Radiosynthesis Services
- Volatile compounds
- Aromatics and heterocyclics
- Chiral compound
- Salt formation
- Amino acids and peptides
- Biomolecules using fermentation (Class 1 containment)
- Covalent radiolabelling techniques with 14C (RadioTag) for macromolecules