CNS/PNS Diseases Animal Models
CNS/PNS Diseases Animal Model Services
Our in vivo pharmacology team is experienced with CNS/PNS disease animal model establishment and validation for efficacy screening, in vivo pharmacology profiling, PDPK and MOA studies. The team is supported by internal PK/Bioanalytical, ex vivo pharmacology and in vitro biology teams to provide integrated services.
Study Types
- Development and validation of disease models
- Maximum tolerated dose studies
- Dose range finding
- Efficacy studies
Capabilities
CNS/PNS Models
- Alzheimer’s disease
- Memory impairment
- Seizure
- Parkinson’s disease
- EAE model
- Depression, anxiety and schizophrenia
- LPS-induced neuroinflammation
- Migraine
- Other neurodegenerative diseases
Analytical Platforms
- Drug exposure in blood and tissue
- Specific biomarkers in blood and tissue levels
- Gene or protein analysis platforms
- FACS analysis of cells, blood and tissue samples
- Histology, biochemistry, IHC
- Blood sample analysis with biochemistry and hematology
- Analysis of body fluid, urine and feces
