CNS/PNS Diseases Animal Model Services

Our in vivo pharmacology team is experienced with CNS/PNS disease animal model establishment and validation for efficacy screening, in vivo pharmacology profiling, PDPK and MOA studies. The team is supported by internal PK/Bioanalytical, ex vivo pharmacology and in vitro biology teams to provide integrated services.

Study Types

Development and validation of disease models
Maximum tolerated dose studies
Dose range finding
Efficacy studies

Capabilities

Oncology Animal Models

Cardiovascular and Metabolic Diseases Animal Models

Inflammation and Pain Animal Models

CNS/PNS Diseases Animal Models

Dermal Animal Models

Ophthalmology Animal Models

Medical Devices Animal Models

A person wearing protective clothing and a mask operates a piece of scientific equipment in a laboratory. They are adjusting a machine with a glowing pink light, labeled "CatWalk XT," used for preclinical ADME studies. The lab features modern devices and maintains a clean, sterile environment.

CNS/PNS Models

Alzheimer’s disease
Memory impairment
Seizure
Parkinson’s disease
EAE model
Depression, anxiety and schizophrenia
LPS-induced neuroinflammation
Migraine
Other neurodegenerative diseases

Close-up of intricate machinery featuring a central metallic component with attached tubes and wires. The equipment, likely used in bioanalytical development, is enclosed in a transparent casing with a faint blue tint. The setup appears to be part of a sophisticated technological or scientific device.

Analytical Platforms

Drug exposure in blood and tissue
Specific biomarkers in blood and tissue levels
Gene or protein analysis platforms
FACS analysis of cells, blood and tissue samples
Histology, biochemistry, IHC
Blood sample analysis with biochemistry and hematology
Analysis of body fluid, urine and feces

Related Services

Scientist in a lab, analyzing tissue samples on dual monitors using advanced imaging technology, representing in vivo pharmacology research.

Learn more about Pharmaron’s animal disease model services

Our in vivo pharmacology team is experienced with disease model establishment and validation for efficacy screening, in vivo pharmacology profiling, PDPK and MOA studies. The team is supported by internal PK/Bioanalytical, ex vivo pharmacology and in vitro biology teams to provide integrated services in various therapeutic areas.

Blue DNA Helix Molecule

Learn more about Pharmaron’s integrated drug discovery and development services

Pharmaron provides a complete integrated platform from drug discovery to proof of concept (“POC”). Our industry knowledge, strong execution tactics and end-to-end solutions shorten the drug discovery and development cycle.