Ophthalmology Animal Models

Ophthalmology Animal Model Services

Pharmaron provides ocular disease animal models to help evaluate compound efficacy in disorders affecting the eye. Combining reliable preclinical disease models with multimodal imaging and histology can progress the pipeline forward. Our scientists are at the forefront of ophthalmic drug development.

We have access to board-certified veterinary ophthalmologists and onsite support from attending veterinarians to ensure the study is conducted in compliance and accordance with animal welfare. Pharmaron has experience with many key ocular disease models, including sophisticated compound delivery in ocular compartments, comprehensive evaluation and imaging for both the front and back of the eye, to help evaluate your drug’s efficacy.

Dose routes: topical, intrastromal, intracameral, intravitreal, suprachoroidal, subretinal, subconjunctival, subtenon

For comprehensive safety profiling, refer to the Ocular Toxicology services page.

A person in a lab coat and blue gloves is pointing at a computer screen displaying various medical scans of eyes over a 12-week period, highlighting findings crucial for bioanalytical development. The individual is in a laboratory setting with scientific equipment in the background.

Ocular Disease Models

  • Glaucoma
  • Choroidal Neovascularization (CNV)
  • Age-Related Macular Degeneration (AMD)
  • Keratoconjunctivitis Sicca (KCS)
  • Allergic conjunctivitis
  • Anterior uveitis
  • Infectious keratitis
  • Neuroprotection
  • Corneal wound healing
  • Diabetic macular edema

Technology for Ocular Evaluation

  • Slit-lamp biomicroscopy with photography
  • Pneumatonometry (IOP measurement)
  • Optical Coherence Tomography
  • Surgical/operating microscope with videography
  • Direct/indirect ophthalmoscopy
  • Phacoemulsion
  • Laser
  • Specular microscopy
  • Color fundus photography
  • Fluorescein Angiography
  • Electroretinography (ERG)
  • Optokinetic response (OKR)
  • Vitrectomy