Genetic Toxicology Services

By using the most advanced GLP study designs and guidelines, along with our innovative and integrated approach, Pharmaron provides genetic toxicology services to evaluate the genotoxic potential in a GLP-compliant manner.

In addition, we help our partners successfully screen their compounds to identify if there is a potential for genetic damage or genotoxic impurities.

Pharmaron’s safety assessment team provides genotoxicity screening assays for discovery programs and standard GLP genotoxicity assays supporting regulatory guidelines and GLP standards.

Capabilities

General Toxicology

Safety Pharmacology

Genetic Toxicology

Developmental and Reproductive Toxicology

Pathology

Specialty Safety Assessment

Bioanalysis

Connect with a Scientific Expert

A scientist in protective gear inserts a sample slide into advanced lab equipment, likely for genetic toxicology analysis. The blue gloves and sterile environment highlight a focus on precision and contamination control.

Genotoxicity Screening Assays

Micro Ames, Mini Ames, Ames
in vitro micronucleus: CHO cell, human lymphocyte, other cell lines
in vitro chromosome aberration: CHO cell, human lymphocyte
Gene mutation: mouse lymphoma
in vivo rodent bone marrow micronucleus
in vivo chromosome aberration in rats
in vivo comet assay in rodent

A scientist holds a petri dish with handwritten labels, preparing for a toxicology experiment. The dish is positioned over a grid plate used for precise analysis, indicating careful observation of test results.

GLP Standard Genotoxicity Assays

Ames
In vitro micronucleus: CHO cell, TK 6 cell, human lymphocyte
Chromosome aberration: CHO cell, human lymphocyte
Gene mutation: mouse lymphoma
In vivo rodent bone marrow micronucleus, independent or integrated into general toxicology studies in rodent

Related Services

Close-up of a microscope lens focusing on a general toxicology slide, capturing detailed tissue analysis in a clinical lab setting.

Learn more about Pharmaron’s safety assessment services

Pharmaron’s experienced team evaluates the safety of new drug candidates from general toxicology, safety pharmacology, genetic toxicology, DART to immunotoxicity and immunogenicity in support of our partner’s IND and NDA submissions worldwide.

Learn more about Pharmaron’s integrated drug discovery and development services

Pharmaron provides a complete integrated platform from drug discovery to proof of concept (“POC”). Our industry knowledge, strong execution tactics and end-to-end solutions shorten the drug discovery and development cycle.