Radiolabelling and Radiosynthesis

Radiosynthesis and radiolabelling services ADME

Radiolabelling and Radiosynthesis Services

Our radiochemistry team provide expert advice on radiosynthesis and preparation and release of radiolabelled test compounds for use in non-clinical and clinical drug development and in environmental fate studies. We offer complete management of the radiosynthesis process, from labelling position selection, optimizing radiosynthetic pathway, final product analysis to repurification and recycling options. We also offer covalent radiolabelling/radio tagging techniques with 3H and 14C for biologics.

Pharmaron Radiosynthesis

Radiosynthesis Services

  • 14C radiosynthesis (custom)
  • 3H radiosynthesis (custom)
  • GMP preparation of 14C radiolabelled drug substance (14C-API) and radiolabelled drug product (investigational medicinal product or IMP)
  • Non-GMP clinical-grade repurified 14C-API (for use in microtracer or microdosing studies)
  • 3H and 14C rapid covalent radio-tagging techniques

Pharmaron Researcher in Lab

Custom Carbon-14 Radiosynthesis Services

  • Volatile compounds
  • Aromatics and heterocyclics
  • Chiral compound
  • Salt formation
  • Amino acids and peptides
  • Biomolecules using fermentation (Class 1 containment)
  • Covalent radiolabelling techniques with 14C (RadioTag) for macromolecules

Download PDF to learn more about Pharmaron’s
Manufacture of 14C Radiolabelled Drug Substances and Drug Products for Clinical Studies.

pdf download for manufacture of carbon-14

Oligonucleotides, Radiolabelling and Metabolism Services

Learn about Pharmaron’s capability to synthesize radiolabelled oligonucleotides.

Research team members working in a lab