Home » Services » Clinical Development » Radiolabelling and Radiosynthesis

Radiolabelling and Radiosynthesis

A scientist wearing blue gloves carefully pours blue liquid from a flask into a test tube in a laboratory setting. The background is blurred, emphasizing the precise handling of chemicals. in radiosynthesis and radiolabelling services for ADME

Radiolabelling and Radiosynthesis Services

Our radiochemistry team provide expert advice on radiosynthesis and preparation and release of radiolabelled test compounds for use in non-clinical and clinical drug development and in environmental fate studies. We offer complete management of the radiosynthesis process, from labelling position selection, optimizing radiosynthetic pathway, final product analysis to repurification and recycling options. We also offer covalent radiolabelling/radio tagging techniques with 3H and 14C for biologics.

Learn more about our Radiolabelled services

Capabilities

Carbon-14 Radiosynthesis
Tritium Radiosynthesis
GMP Carbon-14 Radiolabelled APIs and IMPs
Tritium and Carbon-14 Radiolabels (RadioTag)
A scientist in blue gloves carefully measures a liquid in a graduated cylinder, performing tritium radiolabelling and radiosynthesis under controlled conditions.

Radiosynthesis Services

  • 14C radiosynthesis (custom)
  • 3H radiosynthesis (custom)
  • GMP preparation of 14C radiolabelled drug substance (14C-API) and radiolabelled drug product (investigational medicinal product or IMP)
  • Non-GMP clinical-grade repurified 14C-API (for use in microtracer or microdosing studies)
  • 3H and 14C rapid covalent radio-tagging techniques

A scientist in protective gear works on radiolabelling and radiosynthesis in a lab, surrounded by specialized equipment and fume hoods.

Custom Carbon-14 Radiosynthesis Services

  • Volatile compounds
  • Aromatics and heterocyclics
  • Chiral compound
  • Salt formation
  • Amino acids and peptides
  • Biomolecules using fermentation (Class 1 containment)
  • Covalent radiolabelling techniques with 14C (RadioTag) for macromolecules

Download PDF to learn more about Pharmaron’s
Manufacture of 14C Radiolabelled Drug Substances and Drug Products for Clinical Studies.

Download Now
Promotional PDF for Pharmaron's manufacturing services for Carbon-14 radiolabelled drug substances and products, supporting clinical studies and research.

Oligonucleotides, Radiolabelling and Metabolism Services

Learn about Pharmaron’s capability to synthesize radiolabelled oligonucleotides.

Learn More
Two scientists in protective gear review documents in a lab near a radiolabelling and radiosynthesis workstation with specialized equipment.

Related Services

Blue DNA Helix Molecule

Learn more about Pharmaron’s small molecule services

Pharmaron provides a complete integrated platform from drug discovery to proof of concept (“POC”). Our industry knowledge, strong execution tactics and end-to-end solutions shorten the drug discovery and development cycle.
Small Molecule Services
A row of three Erlenmeyer flasks containing colorful liquids—pink, yellow, and blue—are on a lab bench. In the background, an empty test tube rack and two blurred figures in lab coats are visible within a genetic toxicology laboratory setting.

Learn more about Pharmaron’s laboratory services

Laboratory services at Pharmaron include tech platforms of chemistry (analytical, synthetic, medicinal and computational chemistry), biosciences (in vitro biology, in vivo pharmacology, DMPK and compound management system), safety assessment, bioanalysis, integrated drug discovery (from hit identification to PCC (preclinical candidate) nomination) and medical devices.
Laboratory Services