in vitro Biology Services

Pharmaron’s in vitro biology team supports drug discovery and development programs for the identification of candidate compounds.

The team is highly experienced in target validation, biophysics, biochemistry, phenotype analysis, target engagement, action mechanism exploration and biomarker profiling.

Our team supports various therapeutic areas, including oncology/immuno-oncology, metabolic disorders, immunology/inflammation, and neurologic disorders.

Learn more: in vitro Biology Services Overview

Capabilities

Target Identification and Validation

High-Throughput Screening Service

Cell Line Engineering

Cellular Disease Models

A PerkinElmer plate handler robot in action, moving laboratory plates for automated in vitro biology assays in a streamlined lab environment.

in vitro Biology Solutions from Target Validation to Candidate Selection

Biophysics and other binding assays
Biochemical activity assays
Cell functional/phenotypic screening
Target engagement assays
Mechanism of action studies
Signaling pathway exploration
Protein analysis from single protein to proteomics
Gene analysis from single gene to sequence
PD biomarker profiling and screening
Selectivity panel evaluation
in vitro safety panel assessment

Read about Pharmaron’s approach for uncovering mechanisms of drug resistance in cancer cells

Application note highlighting Pharmaron’s research on elucidating drug resistance mechanisms in cancer cells, focusing on RNA sequencing and pathway identification methods.

Meet Dr. Fang He

Read how Dr. He, Senior Vice President, in vitro Biology, has advanced our in vitro biology capabilities.

Scientist in lab coat standing beside a Beckman Coulter Echo 655 machine, used for in vitro biology research, with lab equipment in the background.

Related Services

Two scientists in lab coats and masks conduct an experiment using a pipette in a biosciences lab, with equipment and supplies on the counter.

Learn more about Pharmaron’s biosciences services

Pharmaron’s in vitro biology, in vivo pharmacology, DMPK and discovery biologics services support drug discovery and early development programs. Integration of these functions, together with laboratory chemistry, CMC and safety assessment, successfully deliver preclinical candidates and IND packages.

Blue DNA Helix Molecule

Learn more about Pharmaron’s integrated drug discovery and development services

Pharmaron provides a complete integrated platform from drug discovery to proof of concept (“POC”). Our industry knowledge, strong execution tactics and end-to-end solutions shorten the drug discovery and development cycle.