DNA-Encoded Libraries
DNA-Encoded Library (DEL) Services
Pharmaron’s state-of-the-art DNA-Encoded Libraries Technology (DELT) platform enables the custom synthesis and screening of billions of compounds against biological targets in a fast and cost-effective way. Built on our strong synthetic and medicinal chemistry foundation, the designed libraries are composed of novel structures. These structures cover a wide chemical space inherently including diversified scaffolds, which are drug-like and ideally suited for further hit-to-lead optimization.
- Novel Chemistry: New chemistry development; leverage unique building block collections
- Library Design: Design bespoke DNA-encoded libraries based on desired specifications
- Library Production: DELs with high quality standards synthesized
- DEL Screening: Billions of compounds screened against targets under multiple conditions
- Hit Analysis: Using informatics for data crunching and selection of promising hits
- Target Production & Assay Development: Additional pre-screening services available
Learn more: Integrated Drug Discovery | Library Synthesis Services
Capabilities
DEL Scientific Resources
- β-Lactam DNA-encoded Libraries
- New Amide Generation Strategies for Higher Quality DELs
- New DEL Design Strategies with Innovative Linkers
- Alkyne Iodination and Acetylenic Couplings on-DNA