in vivo Studies
in vivo Study Services
CGT therapeutics have been proven as a class of important and emerging medical modalities to treat life-threatening diseases. The in vivo disease models established at Pharmaron have been tailored to meet the characteristics of CGT products and can be employed to assist CGT project teams in decision-making on a critical path or a key milestone accomplishment.
Studies using disease models and safety models are often accompanied by PK or TK and/or biomarker studies, biodistribution and viral shedding if the testing CGT products are AAV or viral vector based, which forms the basis of in vivo PK/PD correlation studies.
- Animal disease models
- Safety assessment
- Tissue distribution and viral shedding studies for CGT products