GMP Gene Therapy Manufacturing and QP Release

Two scientists in full protective gear manage a GMP Gene Therapy Manufacturing process, monitoring a large stainless steel bioreactor. One operates a control panel while the other handles tubing connections, ensuring compliance for QP (Qualified Person) release. This process ensures product quality and safety before distribution.

GMP Gene Therapy Manufacturing and QP Release Services

Pharmaron’s Cell and Gene Therapy CDMO (CGT CDMO), located in Liverpool, UK, leverages its industry-leading expertise in process R&D, cGMP manufacturing, and advanced analytical capabilities to support to support our partners across every stage of gene therapy manufacturing.

Our world-class cGMP manufacturing facility is purpose-designed for viral vector manufacture.  We have expertly trained cGMP staff to consistently deliver drug substances to high-quality standards with our ‘right-first-time’ approach.

A scientist in full protective gear operates a large biopharma manufacturing machine, ensuring GMP standards and quality control via a computer interface.

GMP Gene Therapy Manufacturing

  • Up to 500L scale bioreactors
  • Suspension-based cell culture
  • Chromatography-based purification solutions
  • Purpose-built manufacturing facility
  • State-of-the-art manufacturing scale-validated equipment
  • Flexible and independent manufacturing suites
  • cGMP controlled warehouse
  • cGMP-controlled cell bank storage facility
A scientist in full protective gear, including a hairnet and mask, operates equipment in a GMP manufacturing facility. They handle a large stainless steel vessel, ensuring compliance with sterile production protocols.

CGT CDMO Services

  • Starting material production, management and release
  • Phase-appropriate method validation and method transfer
  • Advanced analytical toolkit for process & product characterization
  • Qualified and/or validated in-process monitoring and release testing for GMP release
  • Rapid transition from development to clinical manufacture, utilizing Pharmaron’s established platform processes and multi-skilled process sciences team
  • cGMP controlled storage of cell banks, raw materials and consumables
  • Effective scale-up and technical transfer to one of our GMP viral vector suites