Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point
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Authors: Ward, R; Bethel, P; Cook, C; Davies, E; Debreczeni, J; Fairley, G; Feron, L; Flemington, V; Graham, M; Greenwood, R; Griffin, N; Hanson, L; Hopcroft, P; Howard, T; Hudson, J; James, M; Jones, C; Jones, C; Lamont, S; Lewis, R; Lindsay, N; Roberts, K; Simpson, I; St-Gallay, S; Swallow, S; Tang, J; Tonge, M; Wang, Z; Zhai, B.
J Med Chem. 2017 Apr 27;60(8):3438-3450
DOI: 10.1021/acs.jmedchem.7b00267
Access the publication at:https://pubmed.ncbi.nlm.nih.gov/28376306/