How Does Compaction Analysis Help De-risk Your Projects?
Tablets are a popular oral drug delivery method due to their convenience, patient compliance, precision dosing and relative ease of manufacture. However, preparing a tablet that can be manufactured at a production scale can be challenging. In fact, the transition from laboratory to pilot scale can often lead to delays in bringing your drug to the market. Compaction analysis can help reduce the risk associated with the scale-up process by enabling you to streamline formulation development and achieve a commercial-scale production process more quickly and cost-effectively.
Compaction analysis is a powerful tool that evaluates the ability of a powder mixture to withstand compression forces. By compressing a sample of the powder mixture using specialized instruments, we can measure crucial parameters like porosity, tensile strength and deformation behavior. The analysis provides valuable insights into how the powder will behave during production, enabling informed decisions regarding formulation and process development.
Compaction Analysis Whitepaper
Our whitepaper provides in-depth insights into the benefits of compaction analysis and its role in successful tablet development:
- Introduction to compaction analysis
- API compaction analysis
- Formulation compaction analysis
- How to use compaction analysis to empower better-informed decision-making
Additional Resources
Learn more about how early assessment of compaction properties can de-risk your production scale-up and increase your chances of success, by downloading our poster ‘The use of compaction simulation as a tool to aid successful tablet formulation’ here.
At Pharmaron, we offer integrated end-to-end CMC capabilities tailored to meet your needs at every stage of drug development. Whether you are in the discovery phase, advancing through clinical trials, or preparing for commercialization, our team of experts provides innovative solutions and strategic guidance to maximize the success of your CMC programs. Take the next step in advancing your CMC projects by contacting our experts here.
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