Virtual Lecture: Total Synthesis of Complex, Bioactive Natural Products
Capabilities
Lecture held on: November 8, 2023
Presenter
Prof. Christopher D. Vanderwal – Department of Chemistry, University of California, Irvine, CA, USA
In this lecture, Prof. Christopher D. Vanderwal will describe the long-term efforts to develop efficient syntheses of the antiplasmodial isocyanoterpenes, as well as their analogues, to dig deeper into their potential as antimalarials. The second story will briefly describe how Prof. Vanderwal put forth new hypotheses for biosynthesis of two different, significantly rearranged Strychnos alkaloids, and how our earlier successful synthesis of Strychnos family members permitted the execution of novel, presumably biomimetic, syntheses of the alsmaphorazines and alstonlarsines.