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Poster titled "Development of in vitro potency assays to evaluate early activation, Granzyme B secretion, and cytotoxicity of CAR-T cells," featuring detailed charts and graphs. The background includes purple and blue geometric patterns with the Pharmaron logo in the bottom right corner, underlining their expertise in bioanalytical development. A download button is provided below.

Development of in vitro potency assays to evaluate early activation, Granzyme B secretion, and cytotoxicity of CAR-T cells

CD19-redirected chimeric antigen receptor (CAR) T cells have been successfully used in treating patients with B-cell leukemia. The purpose of this study was to develop in vitro potency assays for determining early activation and cytotoxicity of CAR-T cells.

To learn more about why Forced Degradation studies are a key requirement in the development of any biological product and how Pharmaron can help, please complete the form below to download the poster: AAV Forced Degradation Capabilities.