Bioinformatics

Pharmaron Woman using Echo machine for Bioinformatics Services

Bioinformatics Services

Our bioinformatics services are designed to cater to the diverse needs of our clients, offering a range of applications AI-supported computational drug design, virtual drug screening, target identification, phenotypic studies, and biomarker analysis through to predictions of DMPK in the human body.

in vitro Biology research at Pharmaron is advanced by bioinformatics through analysis of large and complex datasets, facilitating informed decision-making and efficient, data-driven insights.

Our bioinformatics services are tailored to support the specific research objectives of each project, available either as a fee-for-service or seamlessly integrated into the workflow of our client’s drug discovery projects.

We possess extensive experience in the mining, visualization and analysis of disease-focused genomic, proteomic, and phenotypic data to address a wide array of research questions. These include:

  • Determining mechanisms of drug resistance
  • Understanding phenotypic signatures
  • Discovering biomarkers that predict treatment response
  • Identifying pharmacodynamic biomarkers
  • Identifying new targets, neoantigens, and drivers of disease
  • Modeling drug-target interactions
  • Facilitating drug repurposing
Protein networks are identified via bioinformatics analysis of proteomics

Genomic and proteomic data analysis

  • Proteogenomics
  • Variant analysis
  • Differential analysis
  • Enrichment analysis
  • Correlation analysis
  • Protein-protein interaction networks
  • Pathway analysis
  • Clustering and networking analysis
  • Multivariate analysis
high content screening requires bioinformatics analysis services to decipher large datasets

Image and phenotypic analysis

  • Large cell panel screening support
  • Large combination drug testing support
  • Cell painting support
  • High-content imaging support
  • Batch effect visualization
  • Machine learning algorithms
  • Compound clustering
  • Mode of action analysis
  • Mapping of morphological profiles

View the case study: Bioinformatics services supporting the unveiling of drug resistance mechanisms

Digital poster titled "Mechanism of BRAF Inhibitor Resistance Revealed by Cell Panel Screening and Bioinformatics," featuring charts and graphs. Accompanied by the text "Download Below" and the Pharmaron logo in the bottom right corner, this resource delves into genetic toxicology insights.