Publications
Publications
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator
Thomson, C.G., Aicher, T.D., Cheng, W., et al., J. Med. Chem. 2024, 67, 7, 5259–5271.
Publications
Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity
Wang, S., Klein, S.O., Urban, S. et al., Nat. Commun. 2024, 15, 43.
Publications
PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
Stokes, M.E., Calvo, V., Fujisawa, S., et al., Clin. Cancer Res. 2023 Dec 1;29(23): 4870-4882.
Publications
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia
Liu, Y., Li, Q., Alikarami, F., et al., Cancer Discov. 2022 Nov 2;12(11): 2684-2709.
Publications
Completion of the impurity profile of lymecycline: Formal identification of impurities E and F. J.
Billié, S., Reversé, K., Chambon, S., et al., Pharm. Biomed. Anal. 2022 Oct 25; 220:114993.