Publications

Non-specific binding of compounds in in vitro metabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models

Gardner, I., Xu, M., Han, C., et al., Xenobiotica. 2022 Aug; 52(8):943-956.

Publications

Development of on-DNA Formation of Benzofuran for DNA-Encoded Library Synthesis

Luo, A., Zhou, H., Wang, X., Zeng, F., Yu, W., Yang, K., Duchemin, N., and Hu, Y. J. Org. Lett. 2024.

Publications

Discovery of a Novel Series of Selective Macrocyclic PKCTheta Inhibitors

Crosignani, S.; Campos S.; Bouix-Peter, C.; Harris, C.; Talbot, E.; Hu, H.; Wang, S.; Maclean, J.; Zanelli, U.; Taylor, S.; Foote, K.; Hacini-Rachinel, F.; Nicodeme, E.; Julia, V. Bioorganic & Medicinal Chemistry Letters, 2024.

Publications

Development of On-DNA Cyclic Imide Synthesis for DNA Encoded Library Construction

Xue, L.; Zhou, S.; Wu, J.; Duchemin, N.; Chen, B.; Zhang, J.; Zhang, H.; Yang, K.; Hu, Y.J. ChemBioChem, 2023.

Publications

On-DNA Morita-Baylis-Hillman Reaction: Accessing Targeted Covalent Inhibitor Motifs in DNA-Encoded Libraries

Xue, L.; Liu, W.; Li, S.; Duchemin, N.; Lou, M.; Yuan, J.; Zhang, H.; Chen, J.; Yu, W.; Yang, K.; Hu, Y.J. Bioconjugate Chem., 2023.