Publications

Publications

PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors

Stokes, M.E., Calvo, V., Fujisawa, S., et al., Clin. Cancer Res. 2023 Dec 1;29(23): 4870-4882.
Publications

Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia

Liu, Y., Li, Q., Alikarami, F., et al., Cancer Discov. 2022 Nov 2;12(11): 2684-2709.
Publications

Completion of the impurity profile of lymecycline: Formal identification of impurities E and F. J.

Billié, S., Reversé, K., Chambon, S., et al., Pharm. Biomed. Anal. 2022 Oct 25; 220:114993.
Publications

Non-specific binding of compounds in in vitro metabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models

Gardner, I., Xu, M., Han, C., et al., Xenobiotica. 2022 Aug; 52(8):943-956.
Publications

Discovery of a Novel Series of Selective Macrocyclic PKCTheta Inhibitors

Crosignani, S.; Campos S.; Bouix-Peter, C.; Harris, C.; Talbot, E.; Hu, H.; Wang, S.; Maclean, J.; Zanelli, U.; Taylor, S.; Foote, K.; Hacini-Rachinel, F.; Nicodeme, E.; Julia, V. Bioorganic & Medicinal Chemistry Letters, 2024.